Interfocal genomic heterogeneity uncovered
نویسندگان
چکیده
منابع مشابه
Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues.
The long arm of chromosome 10 is frequently affected by allelic loss in prostate cancer. PTEN/MMAC1, a candidate tumor suppressor gene located at 10q23.3, a region commonly deleted in prostate cancer, was recently identified and found to be deleted or mutated in cancer cell lines derived from a variety of human tissues including prostate. To examine the role of PTEN/MMAC1 in the progression of ...
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a Department of Biology, Wesleyan University, Middletown, CT 06459-0170, USA 10 b Department of Biology, University of Virginia, P.O. Box 400328, Charlottesville, VA 2290411 4328, USA 12 * These authors contributed equally to this work. 13 † Present address: Public Interest Network, Boston, MA. 14 ‡ Present address: Department of Biochemistry, University of California, San Francisco, CA. 15 16 ...
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ژورنال
عنوان ژورنال: Nature Reviews Urology
سال: 2018
ISSN: 1759-4812,1759-4820
DOI: 10.1038/s41585-018-0098-6